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Polyubiquitination of signaling molecules such as TRAF2, TRAF6, RIP-1, and NEMO activates the TAK1 and IB kinase (IKK) complexes, leading to NF-B activation and pro-inflammatory cytokine production
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Malignant transformation in a nontumorigenic human prostatic epithelial cell line
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1 Diabetic autonomic neuropathy
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