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Regulatory bodies like the FDA and EMA necessitate thorough physicochemical characterisation, stability information, and proof of therapeutic equivalency, which can be challenging for these heterogeneous systems [124]
of Health and Human Services, 1 November 2007, archived from the original on 2008-02-24, retrieved 29 March 2008 "The facts and fictions of chelation therapy"
The combination has not been studied across extended timeframes in humans
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