However, studies support its use for health, brain function, and disease prevention
doi: 10.1056/NEJMoa2032183 9 WhartonSFreitasPHjelmesthJKabischMKandlerKLingvayIet al
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Zepbound (tirzepatide) is an FDA-approved medication for chronic weight management that works by mimicking natural hormones to reduce appetite and promote weight loss
extended the approach by presenting synNotch ligands on biomaterials, pointing to the possibility of material-guided secretion, while Synthetic Enzyme-Armed KillER Chimeric Antigen Receptor-T platforms demonstrated how engineered immune cells can conditionally secrete prodrug-activating enzymes within the tumor microenvironment 114,115