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For gut issues, oral capsules work well at 500-1,000mcg daily on an empty stomach
It is the medication working exactly as intended
10.1016/s0899-9007(02)00807-9 10 CianfaraniS.GermaniD.RossiP.RossiL.GermaniA.OssiciniC.et al (1998)
Note: This article has been updated to make it clear that Ozempic is not licensed as a weight-loss treatment in the UK.
Karen Mann
Sitagliptin, a dipeptidyl peptidase-4 inhibitor, was selected as an active-comparator placebo proxy because it was recommended in clinical guidelines as a second-line glucose-lowering therapy, had a similar high cost to the study drugs, showed no effect on cardiovascular outcomes in a large randomized controlled trial and has been validated as a placebo proxy in prior claims-based research 20,41
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