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The induction of GLP-1 or its analogs in the liver can regulate varieties of processes, including hepatic gluconeogenesis, glycogen synthesis, and glycolysis [32]
VrintsCAndreottiFKoskinasKCRosselloXAdamoMAinslieJet al2024 ESC guidelines for the management of chronic coronary syndromes: developed by the task force for the management of chronic coronary syndromes of the European Society of Cardiology (ESC) endorsed by the European Association for Cardio-Thoracic Surgery (EACTS)
2.2.3 Beyond the eye In renal tubular cells (Wang et al., 2021) and brain tissue in animal stroke model (He et al., 2020), exenatide and liraglutide activate NAD + -dependent deacetylase SIRT1, reducing mitochondrial dysfunction and oxidative stress by decreasing ROS production, thereby preventing apoptosis induced by lipotoxicity
Hepatitis/Elevated liver enzymes/Jaundice Diabetic retinopathy problems: Changes in vision in those with Type 2 diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy Severe gastrointestinal disease - may cause gastrointestinal disease
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