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The induction of GLP-1 or its analogs in the liver can regulate varieties of processes, including hepatic gluconeogenesis, glycogen synthesis, and glycolysis [32]

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VrintsCAndreottiFKoskinasKCRosselloXAdamoMAinslieJet al2024 ESC guidelines for the management of chronic coronary syndromes: developed by the task force for the management of chronic coronary syndromes of the European Society of Cardiology (ESC) endorsed by the European Association for Cardio-Thoracic Surgery (EACTS)

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2.2.3 Beyond the eye In renal tubular cells (Wang et al., 2021) and brain tissue in animal stroke model (He et al., 2020), exenatide and liraglutide activate NAD + -dependent deacetylase SIRT1, reducing mitochondrial dysfunction and oxidative stress by decreasing ROS production, thereby preventing apoptosis induced by lipotoxicity

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Hepatitis/Elevated liver enzymes/Jaundice Diabetic retinopathy problems: Changes in vision in those with Type 2 diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy Severe gastrointestinal disease - may cause gastrointestinal disease

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& Evans, M

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