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Patients with higher starting blood pressure or insulin resistance often experience bigger improvements

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We isolated intestinal crypts from Satb2 f/f ;Vil cre mice for organoid culture and added PYY, PPAR- agonist (rosiglitazone), or a combination of PYY and rosiglitazone to the organoid culture medium

* GSH-independent activity, ** GSH-dependent activity, *** a slightly different substrate, acetophenone, was used (Board and Anders, 2007), **** k cat /K m in mM 1 .min 1