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A recent study showed that the GLP-1 analog liraglutide exerts a significant improvement of disease activity endpoints, including colonic tissues histological changes and colon weight/length ratio, which might be due to its role in reducing inflammatory cytokines and chemokines, such as chemokine (CC motif) ligand 20 (CCL20), IL-33, and IL-22 (78)
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Previous studies demonstrate that IGF-IR contributes to resistance to various category of cancer therapeutics including chemotherapy, endocrine therapy, radiotherapy and targeted therapy
14 , eabq6146 (2022)
Persidsky, Y., Ramirez, S
