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Novel therapeutics for depression: Lmethylfolate as a trimonoamine modulator and antidepressant augmenting agent
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& Serag, W.M
(Protocolo comn) Dosis tpica: 200-300 mcg/da (en 1-2 dosis)
Louis, Missouri: Elsevier
Imidazo[1,2-a]pyrazine derivatives (Compound 40 ) display moderate lipophilicity, high microsomal stability, favorable brain penetration, and strong in vivo exposure, although bulky R-group substitutions can impair permeability (Bartolom-Nebreda et al., 2014)
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