If you know the deck your opponent is playing and/or can judge the likelihood of this based on available mana, do so and make the best informed choice
Marrow-Gnawer Filling in the silver medal slot is one of my favorite cards of all time, Marrow-Gnawer
STING, THE GLINTING DAGGER Haste is still good in Commander, especially when you have tap abilities
Dethrone attacks the format from the opposite angle: It's better when you're behind, at least in terms of life total
Sliver Swarm - Commander Masters Sliver Swarm, as the name suggests, is a deck thats all about Slivers , a creature type thats relatively minor on its own but buffs every other ally with the same type
Whenever you cast a noncreature spell with mana value 3 or greater, Y'shtola deals 2 damage to each opponent and you gain 2 life