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The main consideration is that mutate requires another creature to get the best result

When an opponent's monster declares an attack: Toss a coin and if the result is heads, negate the attack, and if you do, inflict damage to your opponent equal to half the current ATK of that monster your opponent controls.

German Zera-Ritual Diese Karte wird verwendet, um Zera der Mant als Ritualbeschwrung zu beschwren

Yugi's grandfather also suffers the same fate

[3] With the secret revealed, Yuzu began to see Yuya's brothers, and Yuya suspected the place had something to do with that

You'll still need to wait a few turns to get the most out of Barrowgoyf, but for three mana, it's hard to argue with its efficiency