First strike, haste Whenever Edgar attacks, put a +1/+1 counter on each Vampire you control
The combo is fairly easy to disrupt, you have to go all-in on it and you have to find a way to win that isnt Thopters if thats what youre going to do
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Others, like [c]Sadistic Hypnotist[/c], can only be activated whenever you could cast a sorcery
Goblin Electromancer Another pretty straightforward card that cares about spellcasting
In terms of card choices, there is plenty of flexibility, and Hexing Squelcher is far from a necessity